KRIZONE-S Injection (Ceftriaxone 1gm + Sulbactam 500mg)

KRIZONE-S Injection is a combination antibiotic containing Ceftriaxone, a third-generation cephalosporin antibiotic, and Sulbactam, a beta-lactamase inhibitor. Ceftriaxone acts by inhibiting bacterial cell wall synthesis, leading to bacterial death, while Sulbactam prevents the breakdown of Ceftriaxone by beta-lactamase enzymes produced by resistant bacteria. This combination enhances the antibacterial spectrum and effectiveness against resistant organisms.

KRIZONE-S Injection (Ceftriaxone 1gm + Sulbactam 500mg)
Benefits / Uses:

KRIZONE-S Injection is used in the treatment of moderate to severe bacterial infections such as:

  • Respiratory tract infections (pneumonia, bronchitis)
  • Urinary tract infections
  • Skin and soft tissue infections
  • Intra-abdominal infections
  • Bone and joint infections
  • Bloodstream infections (septicemia)
  • Gynecological infections
  • Post-surgical and hospital-acquired infections
Dosage & Administration
  • Dosage and duration depend on the type and severity of infection and should be decided by the physician.
  • Administered by intravenous (IV) or intramuscular (IM) route.
  • Reconstitution and administration should be done only by trained healthcare professionals.
  • Dose adjustment may be required in patients with hepatic or renal impairment.
  • Complete the full prescribed course to prevent antibiotic resistance.
Caution
  • For bacterial infections only; not effective against viral infections.
  • Contraindicated in patients with known hypersensitivity to cephalosporins, penicillins, or beta-lactam antibiotics.
  • Use with caution in patients with liver or kidney disorders.
  • Possible side effects include injection site pain, diarrhea, nausea, vomiting, rash, or allergic reactions.
  • Discontinue and seek medical advice if severe allergic reactions or persistent diarrhea occur.
  • Use during pregnancy and breastfeeding only if prescribed by a doctor.
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